- 2019-10-16 PODCAST
Podcast at King’s College London
King’s College London has recently released a podcast with CARTANA. In this podcast, Ph.D. student Dr. Xinyi (Beibei) Du discuss Single-cell and Spatial Transcriptomics with our CEO and Co-founder, Dr. Malte Kühnemund.
- 2019-10-03 NEWS
Application Note: Mapping brain cell types with CARTANA in situ sequencing on the Nikon Ti2-E microscope
CARTANA has recently published an application note “Mapping brain cell types with CARTANA in situ Sequencing (ISS) on the Nikon Ti2-E microscope” in Nature Methods, October 2019. In this application, we show in details how CARTANA ISS is used for mapping transcriptional cell types within the spatial context of mouse brain sections and we thought this can benefit your research
- 2019-09-04 NEWS
SME Instrument Phase I
CARTANA was awarded SME Instrument Phase I from Vinnova. The funding will be used for the improvement of the library preparation kit and to adapt it to be used in the application of oncology, especially immuno-oncology, as well as other areas.
- 2019-08-12 NEW PUBLICATION
“Spatial and temporal transcriptomics reveal microglia-astroglia crosstalk in the amyloid-β plaque cell niche of Alzheimer ’s disease ”
Chen W.T., and Craessaerts, K. et al. (BioRxiv, 2019)
In a recent study by Chen et al. on the effect of the amyloid-β plaque formation on Alzheimer’s disease progress, the use of CARTANA’s ISS technology plays a crucial role by providing insight at the single-cell level and making possible to describe induced transcriptional responses of different brain cells with spatial context. For the first time, a more conclusive evidence on the roles of amyloid plaques in the neurodegenerative process was drawn.
- 2019-07-01 NEW PUBLICATION
“Spatio-Temporal Structure of Cell Fate Decisions in Murine Neural Crest ”
Soldatov R, Kaucka M. and Kastriti M.E ( Science, 2019)
In this study of the cell fate decision progress of neural crest cells, In Situ Sequencing by Cartana proved to be a crucial complement to the standard methods of single cell sequencing. For the first time, the molecular logic of cell fate decision involved in these rapidly changing cells was revealed- by the dimensions of time and space.
- 2019-06-10 NEWS
CARTANA, Lunaphore and Stockholm University have started a collaboration on automated Next Generation In Situ Sequencing
The collaboration aims at the integration and automation of CARTANA’s Next Generation In Situ Sequencing (NGISS) on Lunaphore’s microfluidic tissue processor technology that will greatly simplify in situ sequencing workflows in laboratories.
- 2019-05-10 NEWS
Join our webinar on Thursday June 13th at 16:00 [BST].
Single cell analysis technologies have enabled the currently ongoing discovery and classification of cell types in tissues. The next step is to localize the position of these cells and study the spatial relationships within cellular organization of tissues. Our new in situ sequencing (ISS) technology makes it possible to sequence barcoded RNA directly inside tissue sections, fulfilling the need to simultaneously analyze the expression of hundreds of genes within every cell of a tissue section with sub-cellular resolution and high throughput (~10cm2 tissue/week), while preserving the tissue morphology.
- 2018-10-08 NEWS
Innovative Start up Phase II Grant
CARTANA was awarded Innovative Start up Phase II from Vinnova. The funding will be used for the development of the next generation of In Situ Sequencing.
- 2018-10-08 NEWS
CARTANA secures $1M for a tech platform understanding the brain and its diseases
- 2018-10-01 NEW PUBLICATION
Xiaoyan Qian et al.,
The latest publication from the Nilsson lab at Scilifelab and Harris lab at UCL in Biorxiv.
They built a spatial atlas of hippocampal CA1 cell types by in situ sequencing 99 genes in mouse brain sections and demonstrate a probabilistic cell typing method that converts in situ sequencing data into spatial cell type maps.
- 2018-06-01 NEWS
CARTANA NEURO KIT
CARTANA is proud to launch its first product, the NeuroKit. CARTANA’s NeuroKit is an optimized reagent kit that enables the mapping of hundreds of genes and cell types via In Situ Sequencing (ISS) in a single tissue section with high throughput and high sensitivity. Neuro kit.