In this section, we have collected a number of Scientific White Papers where we describe the researcher’s application of our technology and Scientific Publications related to In Situ Sequencing technology. We will continuously add more titles to our current collection.
“Spatio-Temporal Structure of Cell Fate Decisions in Murine Neural Crest ” by Soldatov R, Kaucka M. and Kastriti M.E ( Science, 2019).
In this study of the cell fate decision progress of neural crest cells, In Situ Sequencing by Cartana proved to be a crucial complement to the standard methods of single cell sequencing. For the first time, the molecular logic of cell fate decision involved in these rapidly changing cells was revealed- by the dimensions of time and space.
Ke, et al.: “In situ sequencing for RNA analysis in preserved tissue and cells” (2013, Nature methods)
Grundberg, et al: “In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics” (2013, Oncotarget)
Mignardi, et al: “Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ” (2015, Nucleic Acids Research)
Ke, et al: “Fourth Generation of Next-Generation Sequencing Technologies: Promise and Consequences” (2016, Human Mutation)
Kühnemund, et al: “Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy” (2017, Nature Communications)
Xiaoyan Qian et al., “A spatial atlas of inhibitory cell types in mouse hippocampus“ (2018,
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